INDIANAPOLIS — Carson Wentz threw three touchdown passes and Jonathan Taylor rushed for 172 yards and two scores as Indianapolis beat the New York Jets 45-30.
The Colts ran for 260 yards for the highest-single game total in the NFL this season.
The Jets have lost seven straight night games and also lost quarterback Mike White with an injured right forearm. He watched the final three quarters from the sideline as the Colts built a 28-10 halftime lead.
The Colts also scored the first two TDs of the second half to make it 42-10.
The Colts (4-5) host the Jacksonville Jaguars (1-6) Sunday, Nov. 14 at Lucas Oil Stadium at 1 p.m. ET.
Live blog
Fourth quarter
11:35 p.m. - The Colts have finished off a 45-30 win to move to 4-5 on the season.
Jonathan Taylor finished with 200 yards of total offense, including 172 yards rushing and two touchdowns. Nyheim Hines ran for 74 yards and a touchdown for the Colts, who rushed for a combined 260 yards, the most of any team in the NFL this year.
Carson Wentz completed 22-of-30 passes for 272 yards and three touchdowns in the win.
Michael Pittman led Indy's receivers with five catches for 64 yards and a touchdown.
On defense, Bobby Okereke had 11 total tackles and sealed the win with an interception deep in Colts territory.
11:25 p.m. - The Jets forced a Colts punt, then converted a fourth down from deep in their own territory with 2:41 remaining, down 15.
At the two-minute warning, New York had the ball first-and-10 at the Colts' 43-yard line. George Odum appeared to have an interception with 1:40 to play that would have iced the game, but a pass interference penalty on Rock Ya-Sin kept the drive alive.
On first-and-goal from the Colts' 7, Josh Johnson's pass was tipped by Taylor Stallworth and intercepted by Bobby Okereke.
11:19 p.m. - The Jets tried an onside kick following their touchdown, but Jack Doyle pulled the ball in on a high hop to bring the Colts' offense back on the field.
11:17 p.m. - The Jets found the end zone again on a 22-yard catch-and-run by Ty Johnson with 3:35 to play. The score cut the Colts' lead to 45-30, but took nearly four-and-a-half minutes off the clock.
11:03 p.m. - The Colts got back on the board with 8:01 left in the fourth quarter on Michael Badgley's first field goal of the game, a 39-yard kick that made the score 45-23.
10:54 p.m. - Josh Johnson threw his second touchdown pass of the game, a 13-yarder to Ryan Griffin to cut the Colts' lead to 19 at 42-23 with 11:08 remaining in the game.
Third quarter
10:36 p.m. - The Jets picked up their first first down of the second half, then finally got back to the end zone on a 19-yard pass from Josh Johnson to Elijah Moore, the receiver's second scoring catch of the game.
10:30 p.m. - The Colts defense forced another three-and-out, then wasted no time finding the end zone.
Jonathan Taylor broke free for a 78-yard run on first down and a 42-10 lead. Taylor now has 172 yards rushing and two touchdowns on the night.
10:19 p.m. - After forcing a three-and-out, the Colts take over at the Jets' 40-yard line following an unsportsmanlike conduct penalty on the Jets on a 57-yard Thomas Morstead punt.
Indianapolis opened with a 25-yard pass to Nyheim Hines, then found the end zone two plays later on a pass from Carson Wentz to guard Danny Pinter for a 35-10 lead with 6:54 left in the third quarter.
The catch was the first reception in the Ball State alum's NFL career, though he's been in the end zone before.
10:11 p.m. - Looking like they were headed in for another score, the Jets' defense stuffed Indianapolis on four plays inside the 7-yard line, including stopping Jonathan Taylor from the 2-yard line on a direct snap to turn the ball over on downs.
Indianapolis drove 83 yards in nine plays, but came up empty for the first time in the game.
10:01 p.m. - The Colts start the second half with the ball at their own 16-yard line after Isaiah Rodgers was shaken up after a big hit on the kickoff.
Jonathan Taylor returned to the game after sitting out a series late in the first half with a possible knee injury.
PHOTOS: Colts vs. Jets on Thursday Night Football
Second quarter
9:46 p.m. - The Colts take a 28-10 lead to the locker room and will receive the kickoff to start the second half.
Carson Wentz was 15-of-18 passing for 146 yards and two touchdowns in the first half. Jonathan Taylor led all rushers with 11 carries for 74 yards in the half, followed by Nyheim Hines, who ran for 48 yards. Both Colts running backs found the end zone in the first half.
Taylor, however, left the game with a possible knee injury. His status for the second half is not known at this time.
9:39 p.m. - The Colts took over possession at their own 25-yard line with 1:46 remaining and drove deep into Jets territory with two timeouts.
Carson Wentz threw an 11-yard pass that was caught in the end zone by Michael Pittman before it was knocked away by Marcus Maye and ruled incomplete. After a video review, it was determined Pittman had possession long enough to complete the process of the catch before the ball was knocked out and the Colts had their fourth touchdown in four first-half possessions.
9:25 p.m. - Josh Johnson returned under center for the Jets next drive with starter Mike White remaining on the sideline.
Johnson led the Jets to the Indianapolis 15-yard line when the two-minute warning hit.
The Colts defense stiffened, however, forcing New York to settle for a 33-yard Matt Ammendola field goal to cut their deficit to 21-10 with 1:46 left in the half.
9:18 p.m. - After converting a fourth-and-inches from the 4-yard line, Carson Wentz flipped a shovel pass to tight end Jack Doyle who scored from a yard out to extend the Colts' lead to 21-7 with 4:59 to go before halftime.
The Colts twice extended the nine-play, 46-yard drive by recovering their own fumbles, one by Jonathan Taylor, who pulled in his own loose ball and another by Michael Pittman, which was covered up by Doyle.
9:09 p.m. - Darius Leonard punched the ball free from running back Ty Johnson's arms as he lunged toward a first down. A number of Colts players dove for the loose ball, which was recovered by George Odum, setting Indianapolis up with the ball at the Jets' 46-yard line.
9:05 p.m. - Josh Johnson entered the game at quarterback for the Jets with 13:24 left in the second quarter. Trainers were working on an apparent elbow injury to starting quarterback Mike White.
The Jets listed White's return as questionable for Thursday's game.
9:01 p.m. - Jonathan Taylor carried the ball five times for 51 yards on the Colts' second drive, scoring from 21 yards out to give Indianapolis a 14-7 lead.
In their first two drives, the Colts have run the ball nine times for 101 yards.
First quarter
8:47 p.m. - A 12-yard Jonathan Taylor run to the Jets' 37-yard line brought the first quarter to an end with the score tied at 7-7.
8:46 p.m. - The Jets answered the Colts score with a drive of their own.
After converting a long third down early in the drive, Mike White drove New York 75 yards in eight plays, tying the score on a 19-yard pass to Elijah Moore, who had caught a 26-yard pass the play before.
The touchdown made it a 7-7 game with 3:32 left in the first quarter.
8:31 p.m. - The Colts started their first drive of the game from their own 12-yard-line, opening up with a nine-yard run from Jonathan Taylor, then picked up a first down on an offside penalty on the Jets.
After picking up a third-and-6 on a pass to Michael Pittman, Carson Wentz led the Colts to the New York 34-yard-line where Nyheim Hines broke free on first down for a 34-yard touchdown run and a 7-0 Indianapolis lead.
Wentz was 4-of-5 passing for 36 yards in the eight-play, 88-yard scoring drive.
8:23 p.m. - The Jets won the opening coin toss and elected to receive. New York started the opening drive of the game at their own 10-yard line after a penalty.
Quarterback Mike White completed his first three passes for 23 yards, but then was nearly intercepted by Zaire Franklin and threw incomplete as he was hit by Kwity Paye to force a punt.
Hilton, Mack inactive
The Colts will be without wide receiver T.Y. Hilton and running back Marlon Mack, who were included on the team's inactive list for Thursday's game. Also inactive are defensive end Ben Banogu, tackle Julien Davenport, guard/tackle Will Fries and cornerback Bopete Keyes.
The Jets' inactive list includes Indiana University alum Tevin Coleman, along with wide receiver Corey Davis, quarterbacks Zach Wilson and Joe Flacco, defensive lineman Jonathan Marshall, safety Jarrod Wilson and offensive lineman Laurent Duvernay-Tardif.
Game preview
The Colts have consistently been snubbed by the NFL when it comes to getting primetime games at Lucas Oil Stadium. Only seven current players on the Indianapolis roster were with the Colts when they hosted Denver on Thursday, Dec. 14, 2017.
RELATED: 3 keys to a Colts win over the Jets
The Colts will be wearing their all-blue "Color Rush" uniforms as they look to put last week's overtime loss to AFC South rival Tennessee behind them and focus on getting back on track against the 2-5 Jets.
Here's a preview from the Locked On Colts podcast:
