Two children who originally survived Saturday morning's house fire passed away Sunday afternoon.
The family tells WTHR that 14-year-old Miranda Guerra and 6-year-old Fuentes Guerra died at Riley Children's Hospital Sunday afternoon.
Their aunt says they were taken off of life support after tests revealed there was no brain activity.
Their parents, 47-year-old Lionel "Leo" Guerra and 33-year-old Brandy Guerra, along with their brother and sister, 11-year-old Esteban and 8-year-old Blanquita, died Saturday morning.
"He took care of his kids, that was his main goal," family member Mario Tello said Sunday about Leo.
Mario Tello spent all of Saturday night at the hospital and said he had to come see his uncle Leo's home.
Leo was like a father to Mario and now Mario has his own family. In fact, his little boy felt so moved that he left one of his favorite toy cars at the memorial in front of the house as a way to remember his family.
"This is not a dream, this is a nightmare. This is a total nightmare. You never expect that. You hear it all the time, but I never expected it to come to my side of the family," Tello said.
The impact, however, is felt beyond the Guerra family.
"It's difficult to put into words because so many people tried to help," Indianapolis Mayor Greg Ballard said.
Mayor Ballard on Sunday took personal time to visit the hospital and come to the scene.
"There was a family here; a family that was going to grow up in America. The young kids had everything in front of them and now that's not going to happen. It's very sad," Mayor Ballard said.
Leo's sister says he had just won a battle with cancer. She says his optimism never faded.
"My brother's famous saying was, 'It is what it is' and I know it's no consolation, but the way I'm dealing with this is [that] they're together. My brother Leo was very protective of his children and they're all together. I thank God for that," said Sandra Lopez.
Lopez said she is incredibly thankful to the first responders, dispatchers, and the community for all of their support.
"Firefighters were running left and right with the medics. I think they needed all they needed to do and I appreciate everything that they did," she said.
A sign placed outside the Olney Street home sits with a bible verse that reads "wait for his answers" and that is all the tight-knit family says they can do.
"The family has made it very clear that they are going to continue to look at their faith in God and through prayers move forward," said the Guerra family minister AJ Corrales.
The family plans to set up a memorial fund Monday at a local bank.
Indianapolis Fire Department Captain Rita Reith says the fire department believes the six deaths are the largest single loss of life for a family due to fire in its service district.
The cause of the fire is still being determined. Investigators do not believe was foul play involved. Firefighters say there was no working smoke detector in the home.
Services for the six have been set, a family member tells Eyewitness News.
Visitation is Thursday, March 6 from 4:00 pm to 8:00 pm and Friday, March 7 from 11:00 am to 2:00 pm at New Wineskins Ministries, 4501 West 38th Street, in Indianapolis.
Burial will be Friday at 3:00 pm at New Crown Cemetery.
